Explainer

Prescription abbreviations in India: OD, BD, TDS, HS, SOS and the rest

What OD, BD, TDS, QID, HS, SOS, AC and PC mean on an Indian prescription, where each comes from, which ones cause mistakes and what to write instead.

In short

On an Indian prescription, OD means once a day, BD twice a day, TDS three times a day, QID four times a day, HS at bedtime and SOS only if needed, while AC and PC mean before and after food. Most come from Latin: omni die, bis die, ter die sumendum, quater in die, hora somni, si opus sit, ante cibum and post cibum. A few are known to cause harm, so the US Institute for Safe Medication Practices advises writing 'daily' instead of OD or QD, 'right eye' instead of OD on eye drops, 'units' instead of U or IU, and no trailing zero: 1 mg, never 1.0 mg.

  • OD, BD, TDS and QID say how many times a day; a pattern such as 1-0-1 also says when.
  • HS is bedtime, SOS is only if needed, AC is before food and PC is after food.
  • OD can mean once a day or the right eye: on drops, write the eye in words; elsewhere, add the pattern (1-0-0) or write 'daily'.
  • Write 'units' in full, 'mcg' rather than µg, and never 1.0 mg or .5 mg.
  • Many patients can't read this shorthand: add a plain line in their own language.

Prescription shorthand is a working language between the doctor and the chemist. It saves time on a busy OPD morning, and most of the time it is read the way it was meant. This page is a reference for both sides of the counter, and for doctors in their first years of practice: the abbreviations you will meet on Indian prescriptions, where each one comes from, what it means, and the few that have caused mistakes, some of them harmful, because they can be read two ways.

This is general information. Always take medicines as your own doctor wrote them, and ask your doctor or pharmacist if anything is unclear.

What do OD, BD, TDS and the other timing abbreviations mean?

These say how often, and sometimes when, to take a medicine. The Latin below is taken from the UK’s Patient.info prescribing guidance and a list from the US state of Minnesota.

Abbreviation Latin Meaning On Indian prescriptions
OD omni die Once a day Common shorthand for once daily. 1-0-0 if it’s taken in the morning, 0-0-1 at night. On eye drops, OD can also mean the right eye.
BD (or BID) bis die, or bis in die Twice a day Usually one dose in the morning and one at night, the same as 1-0-1
TDS (or TID) ter die sumendum, or ter in die Three times a day Morning, afternoon and night, the same as 1-1-1
QID (or QDS) quater in die, or quater die sumendum Four times a day The same as 1-1-1-1
HS hora somni At bedtime One dose at night, just before sleep
SOS si opus sit If needed Only when the problem is there, such as pain or fever
PRN pro re nata As needed Means the same as SOS
STAT statim At once One dose straight away, usually given in the clinic or ward
AC ante cibum Before food Also written BF or “before food”
PC post cibum After food Also written AF, A/F or “after food”
Q4H, Q6H, Q8H quaque … hora Every 4, 6 or 8 hours By the clock; ask whether night doses are meant

You will also see English shorthand with no Latin behind it: BBF and ABF for before and after breakfast, ES for an empty stomach, and “x 5d” or “5d” for five days. BF deserves a second look: on its own it usually means before food, but in “after BF” it means breakfast. The number patterns themselves, such as 1-0-1 and ½-0-½, have a guide of their own.

Abbreviations for the form, the route and the side

Abbreviation Latin Meaning
Rx or R/ recipe (“take”) Where the medicines start
Tab tabella Tablet
Cap capsula Capsule
Syp or Syr syrupus Syrup
Inj injectio Injection
Gtt guttae Drops; E/D is eye drops
Ung or Oint unguentum Ointment
PO per os By mouth
SL Under the tongue
IV, IM, SC Into a vein, into a muscle, under the skin
OD, OS, OU oculus dexter, oculus sinister, oculus uterque Right eye, left eye, both eyes
AD, AS, AU auris dextra, auris sinistra, auris utraque Right ear, left ear, both ears
RE, LE, BE Right eye, left eye, both eyes, in English

The World Health Organization’s Guide to Good Prescribing explains that the R/ at the top comes from recipe, Latin for “take”, and the S (signa, “write”) marks the directions to be copied onto the label. The other Latin is from the Minnesota list. Around the medicines you will also see English shorthand for the notes: c/o (complains of), k/c/o (known case of), h/o (history of), Dx (diagnosis), Inv (investigations), Adv (advice) and F/U (follow-up).

Which abbreviations cause mistakes?

The ISMP List of Error-Prone Abbreviations, Symbols, and Dose Designations (2024 edition) collects shorthand that was reported to the US Institute for Safe Medication Practices after it was misread, in errors that harmed patients or could have. ISMP says none of it should be used anywhere: not in handwritten or electronic prescriptions, not on labels, not on screens. These are the entries most likely to appear on an Indian prescription, with two more from an Indian hospital’s own list:

Written Meant Can be read as Write instead
OD Once a day Right eye; ISMP’s list records oral liquid medicines being put into the eye “Daily” or “once a day”
OD, OS, OU Right, left or both eyes Right, left or both ears (AD, AS, AU), and the other way round “Right eye”, “left eye”, “both eyes”
QD Every day QID, four times a day “Daily”
QOD Every other day Daily, or four times a day “Every other day”, with the days
HS At bedtime Half-strength “At bedtime”
BD and BT Twice a day; bedtime Each other “Twice a day”; “at bedtime”
U or IU Units U as a 0 or a 4 (4U read as 40); IU as IV or 10 “Units”
µg Microgram mg, a thousand times more “mcg”
1.0 mg 1 mg 10 mg “1 mg”
.5 mg 0.5 mg 5 mg “0.5 mg”
1/2 tablet Half a tablet 1 or 2 tablets “Half tablet”
TIW, BIW 3 or 2 times a week 3 or 2 times a day “3 times a week”, with the days
x1 Once For one day “1 dose”
tsp Teaspoon Tablespoon mL
MTX, HCT Methotrexate, hydrocortisone Mitoxantrone, hydrochlorothiazide The full generic name

The HS and BD rows come from the “never use” list in the study described below; the Minnesota list also warns that HS can mean half-strength. Six entries in the table (U, IU, QD, QOD, the trailing zero and the missing leading zero) are on the US Joint Commission’s “Do Not Use” list too, which ISMP marks on its own list. ISMP even prefers mL, with a capital L, to ml, so that the l can’t be taken for a 1.

Shortened drug names deserve a word. ISMP’s advice is to avoid abbreviating drug names entirely, and India’s 2002 ethics regulations already ask, in clause 1.5 as amended in 2016, for generic names written “legibly and preferably in capital letters”. PCM can stay in your head; PARACETAMOL goes on the paper.

Do these mistakes happen in Indian hospitals?

They do, and a short “never use” list helps, if only a little. A team from AIIMS New Delhi reviewed inpatient prescriptions at an apex tertiary care public hospital and found error-prone abbreviations at an incidence of 47.5%. They drew up a 12-item “never use” list from ISMP’s list and the Australian Commission on Safety and Quality in Health Care’s, put it up on posters in the wards and taught the doctors. The incidence fell to 43.6%, as the study reported in Current Drug Safety in 2023. The preprint’s tables show the commonest offenders: “Inj” for injection, BD for twice a day and OD for once daily. The fall was clear in medicine and surgery and close to nothing in paediatrics, and the authors ask for more: fuller teaching, pocket cards and a policy that forbids these abbreviations.

Legible doesn’t mean understood, either. At a tertiary care government hospital in Kolkata, 96% of 380 patients’ prescriptions were legible, yet only 40% of the patients had a good grasp of how often to take their medicines. Every participant could read English and Bengali. The authors suggest the reason: frequency abbreviations such as BD “are not explained to the patients”, while the number of days “is written as a number, which they understood better”. The abbreviation that a chemist reads at a glance can still be a puzzle at home.

How to write it so nobody has to guess

  1. Say how often in words, or as a pattern with words: “1-0-1, morning and night” rather than BD alone. ISMP advises “daily” instead of OD or QD; if you keep OD, never leave it on its own: add the pattern, as in OD (1-0-0).
  2. Put the eye and the ear in words on drops: “right eye”, “left eye”, “both eyes”.
  3. Write the food instruction and the days in full: “after food, for 5 days”, “half an hour before breakfast”.
  4. Give every SOS its limits: what it is for, the most in a day and the gap between doses. WHO’s Guide to Good Prescribing asks for the maximum dose and the minimum dose interval whenever a medicine is “as required”.
  5. Write “units” in full, and micrograms as mcg (never µg); put a zero before a decimal point (0.5 mg) and never after one (1 mg, not 1.0 mg).
  6. Name the day for weekly and alternate-day doses: “once a week, every Sunday”.
  7. Add one line in the patient’s language. WHO’s guide prefers the local language to Latin and asks for the directions in lay language, without abbreviations or “as directed”. Our Hindi phrases for prescriptions are ready to copy.

If your hospital keeps an approved abbreviation list, put its never-use part where prescriptions are written, as the AIIMS team did. ISMP’s own advice is plain: if you use an uncommon or ambiguous abbreviation, define it.

Where DrMate Rx fits

DrMate Rx, our prescription pad, lets you keep typing the shorthand you already use and prints a complete line from it. Type pcm 650 1-0-1 5d af and the line prints as Tab PARACETAMOL 650 mg, with 1 tab, BD (1-0-1), after food and 5 days in their own columns and “Qty: 10 tabs” under it. Lower on the page, a line of Hindi for the patient reads “Paracetamol 650 mg: 1 गोली, दिन में दो बार, खाने के बाद, 5 दिन तक” (1 tablet, twice a day, after food, for 5 days). The paper never says “pcm”.

On eye drops, it reads OD as the right eye only when the line also says how often: moxicip e/d 1 drop qid od 7d is the right eye, four times a day, while latanoprost 1 drop od be names both eyes, so OD there is once a day. When the line could mean either, as in moxicip e/d 1 drop od 7d, it asks one question, “Is OD the right eye, or once a day?”, and never guesses. It also keeps BBF (before breakfast) apart from BF (before food). If you would rather talk than type, the doctor’s room drafts the prescription from the consultation for you to approve. Either way, the rules on what a prescription must show still apply, and the pad prints in that format.

Questions people ask

What does BD mean on a prescription?

BD means twice a day, from the Latin bis die. On Indian prescriptions it usually means one dose in the morning and one at night, the same as 1-0-1. BID means the same thing.

What is the difference between OD and BD?

OD is once a day and BD is twice a day. On eye drops, OD can also mean the right eye (oculus dexter), which is why medication-safety groups advise writing 'daily' or 'right eye' in words instead.

What does SOS mean on a prescription?

SOS means only if needed, from the Latin si opus sit. A safe SOS line also says what the medicine is for, the most you can take in a day and how long to wait between doses. If yours doesn't, ask your doctor.

What does HS mean on a prescription?

HS means at bedtime, from the Latin hora somni: one dose at night, just before you sleep. Because HS has also been read as half-strength, a team from AIIMS New Delhi put it on their hospital's 'never use' list.

Is TDS the same as TID?

Yes. Both mean three times a day: TDS comes from ter die sumendum and TID from ter in die. On Indian prescriptions TDS usually means morning, afternoon and night, the same as 1-1-1.

Sources

  1. ISMP List of Error-Prone Abbreviations, Symbols, and Dose Designations. Institute for Safe Medication Practices (ISMP, US), an ECRI affiliate, 2024.
  2. General prescribing guidance. Patient.info (UK professional reference, updated by Dr Hayley Willacy, peer reviewed by Dr Colin Tidy), 2024.
  3. Partial list of prescription abbreviations. State of Minnesota (US), health licensing boards (mn.gov), 2012.
  4. Guide to Good Prescribing: A practical manual (WHO/DAP/94.11). World Health Organization, Action Programme on Essential Drugs, 1994.
  5. Thachaparambil, Kausar, Mahesh R and Sharma: Impact of 'Never Use' Abbreviations (Error-Prone Abbreviations-EPA's) List on the Incidence of EPAs in Inpatient Medical Prescriptions in Apex Tertiary Care Public Hospital in India. Current Drug Safety, 18(3), 318-322 (record on PubMed), 2023.
  6. Impact of never use abbreviations (Error Prone Abbreviations-EPAs) list on incidence of EPAs in inpatient medical prescriptions in apex tertiary care public hospital in India (preprint, version 2). medRxiv, 2020.
  7. Das, Kotal and Chatterjee: How well do patients understand medication information written in prescriptions? A study from Eastern India. Indian Journal of Pharmacology, 57(2), 83-89, 2025.
  8. Indian Medical Council (Professional Conduct, Etiquette and Ethics) Regulations, 2002 (amended up to 8 October 2016). Medical Council of India, published by the National Medical Commission, 2016.

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